^a苯甲酰氧芍药甙 ^bBenzoyloxypaeoniflorin
有效成分: ^a苯甲酰氧芍药甙 ^bBenzoyloxypaeoniflorin
异名: 无
化学名: β-D-Glucopyranoside, tetrahydro-5-hydroxy-5b-[[(4-hydro-xybenzoyl)oxy]methyl]-2-methyl-2, 5-methano-1H-3, 4-dioxacyclobuta[cd]pentalen-la(2H)-y1 6-benoate, [1aR-(1aα, 2β, 3aα, 5α, 5aα, 5bα)]-
结构式: str-0149
分子式/分子量: ^aC↓30H↓32O↓13; ^b600.56
临床: 具有抑制纤熔酶作用。
成分分类: 萜类
物理性状: 白色粉末, [α]↑14↓D -10.3°(C=0.37, 甲醇)。UVλ↑EtoH↓max nm(ε): 210 (17000), 215 (肩峰, 15900), 231 (14400), 236 (肩峰, 13600), 259.5 (17300), 273 (肩峰, 11200); IRν↑KBr↓max cm↑-1: 3400 (br.), 1713, 1610, 1593, 1456, 1282; NMR((CD↓3)↓2CO)δ: 1.24 (3H, s), 4.64 (2H, s), 5.33 (1H, s, 缩醛质子), 6.88, 7.88 (4H, A↓2B↓2q, J=9), 7.44？7.61 (3H, m), 7.91？8.08 (2H, m); ↑13CNMR(C↓5D↓5N)δ: C-1 (88.8, s), C-2 (85.9, s), C-3 (44.6, t), C-4 (105.8, s), C-5 (43.7), C-6 (71.6, s), C-7 (22.8, t), C-8 (60.6, t), C-9 (101.6, d), C-10 (19.7, q), C-1' (100.1, d), C-2' (74.7, d), C-3' (78.0, d), C-4' (71.4, d), C-5' (74.9, d), C-6' (65.0, t), C-1'' (121.1, s), C-2'' (132.3, d), C-3'' (116.0, d), C-4'' (163.5, S), C-5'' (116.0, d), C-6'' (132.3, d), C-7'' (166.6, s), C-1''' (130.7, s), C-2''' (129.8, d), C-3''' (128.8, d), C-4''' (133.3, d), C-5''' (128.8, d), C-6''' (129.8, d), c-7''' (166.3, s)↑[1]。
来源: ^a毛茛科植物^b牡丹 Paeonia moutan Sim. ^c根皮↑[1]
作用: 具有抑制纤溶酶和纤溶酶原作用, 作用较牡丹强↑[2]。
参考文献: 1. 生药学杂志 (日) 33(3):171？177, 1979 2. 生药血杂志 (日) 33(3): 178, 1979
用途分类: 作用于酶类及其他生化物质